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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC14 All Species: 8.18
Human Site: S582 Identified Species: 18
UniProt: Q96N46 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96N46 NP_597719.1 770 88319 S582 D R C P L S S S S L E I P D D
Chimpanzee Pan troglodytes XP_001153924 699 78757 H524 E D A L Q K L H K Y M Q K S L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535814 769 87731 S581 E K D R C S L S S S S V E I P
Cat Felis silvestris
Mouse Mus musculus Q9CSP9 761 86774 L572 V K E K E R G L L T S S G E V
Rat Rattus norvegicus NP_001101136 768 87190 L579 K E K E K G L L T S S V E V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506381 699 78865 S524 D S K D P S G S C N S Q A S S
Chicken Gallus gallus NP_001006552 788 90187 T590 R H C S L S R T S G D D E D T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001014336 664 75110 K489 S T S R K K S K K R K H K R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGU5 872 99852 R690 S R S R S R S R S R S R S R S
Honey Bee Apis mellifera XP_001121860 1247 141959 S694 N D I A S P L S N A E K L A E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791418 1698 191424 S746 K R T R S S S S V F E E S A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.5 N.A. 90.5 N.A. 86.4 86.4 N.A. 64 62.6 N.A. 51.8 N.A. 23.5 22.3 N.A. 21
Protein Similarity: 100 77.5 N.A. 94.2 N.A. 91.6 92 N.A. 74.5 76.1 N.A. 66.4 N.A. 41.6 37.2 N.A. 31.4
P-Site Identity: 100 0 N.A. 20 N.A. 0 0 N.A. 20 33.3 N.A. 6.6 N.A. 20 13.3 N.A. 40
P-Site Similarity: 100 6.6 N.A. 40 N.A. 13.3 13.3 N.A. 20 46.6 N.A. 13.3 N.A. 20 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 0 10 0 0 10 19 0 % A
% Cys: 0 0 19 0 10 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 19 19 10 10 0 0 0 0 0 0 10 10 0 19 19 % D
% Glu: 19 10 10 10 10 0 0 0 0 0 28 10 28 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 19 0 0 10 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 10 0 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 10 0 10 0 % I
% Lys: 19 19 19 10 19 19 0 10 19 0 10 10 19 0 0 % K
% Leu: 0 0 0 10 19 0 37 19 10 10 0 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % N
% Pro: 0 0 0 10 10 10 0 0 0 0 0 0 10 0 19 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 19 0 0 0 % Q
% Arg: 10 28 0 37 0 19 10 10 0 19 0 10 0 19 10 % R
% Ser: 19 10 19 10 28 46 37 46 37 19 46 10 19 19 19 % S
% Thr: 0 10 10 0 0 0 0 10 10 10 0 0 0 0 10 % T
% Val: 10 0 0 0 0 0 0 0 10 0 0 19 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _